Search Ontology:
ChEBI

afatinib dimaleate

Term ID
CHEBI:76003
Synonyms
  • (2E)-N-{4-[(3-chloro-4-fluorophenyl)amino]-7-[(3S)-tetrahydrofuran-3-yloxy]quinazolin-6-yl}-4-(dimethylamino)but-2-enamide di[(2Z)-but-2-enedioate]
  • Afatinib maleate
  • BIBW 2992MA2
  • Gilotrif
Definition
A maleate salt obtained by combining afatinib with two molar equivalents of maleic acid. Used for the first-line treatment of patients with metastatic non-small cell lung cancer.
References
  • CAS:850140-73-7
  • DrugBank:DB08916
  • KEGG:D09733
  • PMID:23982599
  • Patent:US2005085495
  • Patent:WO2012121764
  • Patent:WO2013052157
  • Reaxys:14383062
  • Wikipedia:Afatinib
Ontology
ChEBI  ( EBI )
Relationships
is a type of
has_part
has_role
Phenotype
Phenotype resulting from afatinib dimaleate
Phenotype where environments contain afatinib dimaleate
Phenotype modified by environments containing afatinib dimaleate
Human Disease / Model Data
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