neurotensin

Term ID

CHEBI:7542

Synonyms

5-oxo-L-Pro-L-Leu-L-Tyr-L-Glu-L-Asn-L-Lys-L-Pro-L-Arg-L-Arg-L-Pro-L-Tyr-L-Ile-L-Leu
5-oxo-L-Pro-L-Leu-L-Tyr-L-Glu-L-Asn-L-Lys-L-Pro-L-Arg-L-Arg-L-Pro-L-Tyr-L-Ile-L-Leu-OH
5-oxo-L-prolyl-L-leucyl-L-tyrosyl-L-alpha-glutamyl-L-asparaginyl-L-lysyl-L-prolyl-L-arginyl-L-arginyl-L-prolyl-L-tyrosyl-L-isoleucyl-L-leucine
Glp-Leu-Tyr-Glu-Asn-Lys-Pro-Arg-Arg-Pro-Tyr-Ile-Leu-OH
L-Pyr-L-Leu-L-Tyr-L-Glu-L-Asn-L-Lys-L-Pro-L-Arg-L-Arg-L-Pro-L-Tyr-L-Ile-L-Leu
L-pyroglutamyl-L-leucyl-L-tyrosyl-L-alpha-glutamyl-L-asparagyl-L-lysyl-L-prolyl-L-arginyl-L-arginyl-L-prolyl-L-tyrosyl-L-isoleucyl-L-leucine
neurotensin
neurotensin (1-13)
neurotensin 1-13
neurotensin-(1-13)
Pyr-Leu-Tyr-Glu-Asn-Lys-Pro-Arg-Arg-Pro-Tyr-Ile-Leu

Definition

A 13 amino acid peptide hormone which is found in the central nervous system and the gastrointestinal tract. It behaves as a neurotransmitter in the brain, as a hormone in the gut, and also as a neuromodulator. It is implicated in the pathophysiology of several CNS disorders (including schizophrenia, Parkinson's disease, drug abuse, pain, cancer, inflammation, eating disorders and central control of blood pressure) due to its association with a wide variety of neurotransmitter systems such as dopaminergic, sertonergic, glutamatergic, GABAergic, and cholinergic systems.

References

Ontology

ChEBI ( EBI )

Resources

CTD

Relationships

is a type of: peptide hormone

peptide hormone Show first 5 Terms
has_role: human metabolite mitogen neurotransmitter vulnerary

human metabolite mitogen neurotransmitter vulnerary Show first 5 Terms
inverse is_conjugate_acid_of: neurotensin(1+)

neurotensin(1+) Show first 5 Terms
is_conjugate_base_of: neurotensin(1+)

neurotensin(1+) Show first 5 Terms

Phenotype

Phenotype resulting from neurotensin

Phenotype where environments contain neurotensin

Phenotype modified by environments containing neurotensin

Human Disease Model