Search Ontology:
ChEBI

5-[2-(feruloyl)ethen-1-yl]thalidomide

Term ID
CHEBI:74774
Synonyms
  • 2-(2,6-dioxopiperidin-3-yl)-5-[(1E,4E)-5-(4-hydroxy-3-methoxyphenyl)-3-oxopenta-1,4-dien-1-yl]-1H-isoindole-1,3(2H)-dione
  • 5-[(1E,4E)-5-(4-hydroxy-3-methoxyphenyl)-3-oxopenta-1,4-dien-1-yl]thalidomide
Definition
A dicarboximide that is thalidomide substituted at position 5 by an ethenyl group, which in turn is substituted by a feruloyl group at position 2. The compound is a hybrid based on the structures of thalidomide and curcumin and has been found to exhibit cytotoxicity against human multiple myeloma cells.
References
Ontology
ChEBI  ( EBI )
Relationships
is a type of
has_functional_parent
has_role
Phenotype
Phenotype resulting from 5-[2-(feruloyl)ethen-1-yl]thalidomide
Phenotype where environments contain 5-[2-(feruloyl)ethen-1-yl]thalidomide
Phenotype modified by environments containing 5-[2-(feruloyl)ethen-1-yl]thalidomide
Human Disease Model