nafarelin

Term ID

CHEBI:7445

Synonyms

(2S)-N-(2-amino-2-oxoethyl)-1-{(2S,5S,8R,11S,14S,17S,20S)-2-(3-carbamimidamidopropyl)-11-(4-hydroxybenzyl)-14-(hydroxymethyl)-20-(1H-imidazol-4-ylmethyl)-17-(1H-indol-3-ylmethyl)-5-(2-methylpropyl)-8-(naphthalen-2-ylmethyl)-4,7,10,13,16,19,22-heptaoxo-22-
5-oxo-L-prolyl L-histidyl-L-tryptophyl-L-seryl-L-tyrosyl-3-(2-naphthyl)-D-alanyl-L-leucyl-L-arginyl-L-prolylglycinamide
[6-D-(2-naphthyl)alanine]-GnRH
L-pyroglutamyl-L-histidyl-L-tryptophyl-L-seryl-L-tyrosyl-3-(2-naphthyl)-D-alanyl-L-leucyl-L-arginyl-L-prolyl-glycinamide
nafarelin
nafarelina
nafareline
nafarelinum

Definition

An oligopeptide comprising of 5-oxo-L-proline, L-histidine, L-tryptophan, L-serine, L-tyrosine, 3-(2-naphthyl)-D-alanine, L-leucine, L-arginine and L-prolylglycinamide residues joined sequence by peptide linkages. It is a gonadotropin releasing hormone agonist that is used to treat central precocious puberty in children and endometriosis in women.

References

Ontology

ChEBI ( EBI )

Resources

CTD

Relationships

is a type of: oligopeptide

oligopeptide Show first 5 Terms
has_role: anti-estrogen gonadotropin releasing hormone agonist

anti-estrogen gonadotropin releasing hormone agonist Show first 5 Terms
inverse has_part: nafarelin acetate

nafarelin acetate Show first 5 Terms

Phenotype

Phenotype resulting from nafarelin

Phenotype where environments contain nafarelin

Phenotype modified by environments containing nafarelin

Human Disease / Model Data