Search Ontology:
ChEBI

cobicistat

Term ID
CHEBI:72291
Synonyms
  • 1,3-thiazol-5-ylmethyl [(2R,5R)-5-{[(2S)-2-({[(2-isopropyl-1,3-thiazol-4-yl)methyl](methyl)carbamoyl}amino)-4-(morpholin-4-yl)butanoyl]amino}-1,6-diphenylhexan-2-yl]carbamate
  • cobicistat
  • cobicistatum
  • GS 9350
  • GS-9350
Definition
A monocarboxylic acid amide obtained by formal condensation of the carboxy group of (2S)-2-({[(2-isopropyl-1,3-thiazol-4-yl)methyl](methyl)carbamoyl}amino)-4-(morpholin-4-yl)butanoic acid with the amino group of 1,3-thiazol-5-ylmethyl [(2R,5R)-5-amino-1,6-diphenylhexan-2-yl]carbamate. Acts as a pharmacoenhancer in treatment of HIV-1 by inhibiting P450 enzymes that metabolise other medications..
References
Ontology
ChEBI  ( EBI )
Relationships
is a type of
has_role
inverse has_part
Phenotype
Phenotype resulting from cobicistat
Phenotype where environments contain cobicistat
Phenotype modified by environments containing cobicistat
Human Disease Model