Search Ontology:
ChEBI
cobicistat
- Term ID
- CHEBI:72291
- Synonyms
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- 1,3-thiazol-5-ylmethyl [(2R,5R)-5-{[(2S)-2-({[(2-isopropyl-1,3-thiazol-4-yl)methyl](methyl)carbamoyl}amino)-4-(morpholin-4-yl)butanoyl]amino}-1,6-diphenylhexan-2-yl]carbamate
- cobicistat
- cobicistatum
- GS 9350
- GS-9350
- Definition
- A monocarboxylic acid amide obtained by formal condensation of the carboxy group of (2S)-2-({[(2-isopropyl-1,3-thiazol-4-yl)methyl](methyl)carbamoyl}amino)-4-(morpholin-4-yl)butanoic acid with the amino group of 1,3-thiazol-5-ylmethyl [(2R,5R)-5-amino-1,6-diphenylhexan-2-yl]carbamate. Acts as a pharmacoenhancer in treatment of HIV-1 by inhibiting P450 enzymes that metabolise other medications..
- References
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- CAS:1004316-88-4
- Drug_Central:4299
- PMID:20043009
- PMID:20683270
- PMID:21348537
- PMID:22732469
- PMID:22766666
- PMID:22833060
- PMID:22850510
- PMID:22886031
- PMID:23136357
- PMID:23243633
- Patent:US2010256366
- Patent:WO2008010921
- Patent:WO2012151165
- Reaxys:13088386
- Wikipedia:Cobicistat
- Ontology
- ChEBI ( EBI )
- is a type of
-
- has_role
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- inverse has_part
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Phenotype
Phenotype resulting from cobicistat
Phenotype where environments contain cobicistat
Phenotype modified by environments containing cobicistat
Human Disease Model