Search Ontology:
ChEBI
tofacitinib
- Term ID
- CHEBI:71200
- Synonyms
-
- 3-{(3R,4R)-4-methyl-3-[methyl(7H-pyrrolo[2,3-d]pyrimidin-4-yl)amino]piperidin-1-yl}-3-oxopropanenitrile
- CP 690550
- CP-690550
- Tasocitinib
- tofacitinib
- tofacitinibum
- Definition
- A pyrrolopyrimidine that is pyrrolo[2,3-d]pyrimidine substituted at position 4 by an N-methyl,N-(1-cyanoacetyl-4-methylpiperidin-3-yl)amino moiety. Used as its citrate salt to treat moderately to severely active rheumatoid arthritis.
- References
-
- CAS:477600-75-2
- Drug_Central:4713
- KEGG:D09970
- LINCS:LSM-1227
- PDBeChem:MI1
- PMID:21952978
- PMID:21971513
- PMID:22006202
- PMID:22147632
- PMID:22233204
- PMID:22357358
- PMID:22460142
- PMID:22474037
- PMID:22525048
- PMID:22576568
- PMID:22591402
- PMID:22607178
- PMID:22607938
- PMID:22682022
- PMID:22802024
- PMID:22873530
- PMID:22873531
- PMID:22894574
- PMID:22899318
- PMID:22916341
- PMID:22924949
- PMID:22960764
- PMID:23055694
- PMID:23150969
- PMID:23150970
- PMID:23150971
- Patent:WO2007012953
- Patent:WO2007107318
- Patent:WO2010123919
- Reaxys:11647225
- Wikipedia:Tofacitinib
- Ontology
- ChEBI ( EBI )
- is a type of
-
- has_role
-
- inverse has_part
-
Show first 5 Terms
Phenotype
Phenotype resulting from tofacitinib
Phenotype where environments contain tofacitinib
Phenotype modified by environments containing tofacitinib
Human Disease Model