Search Ontology:
ChEBI
midodrine
- Term ID
- CHEBI:6933
- Synonyms
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- (+-)-2-amino-N-(beta-hydroxy-2,5-dimethoxyphenethyl)acetamide
- 1-(2',5'-Dimethoxyphenyl)-2-glycinamidoethanol
- 2-Amino-N-(2,5-dimethoxy-beta-hydroxyphenethyl)acetamide
- DL-N1-(beta-Hydroxy-2,5-dimethoxyphenethyl)glycinamid
- midodrina
- midodrine
- midodrinum
- rac-N-[2-(2,5-dimethoxyphenyl)-2-hydroxyethyl]glycinamide
- Definition
- An aromatic ether that is 1,4-dimethoxybenzene which is substituted at position 2 by a 2-(glycylamino)-1-hydroxyethyl group. A direct-acting sympathomimetic with selective alpha-adrenergic agonist activity, it is used (generally as its hydrochloride salt) as a peripheral vasoconstrictor in the treatment of certain hypotensive states. The main active moiety is its major metabolite, deglymidodrine.
- References
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- CAS:42794-76-3
- DrugBank:DB00211
- Drug_Central:1803
- HMDB:HMDB0014356
- KEGG:C07890
- KEGG:D08220
- LINCS:LSM-1815
- PMID:11096750
- PMID:15273244
- PMID:16676655
- PMID:17901021
- PMID:18410283
- PMID:18840368
- PMID:19522958
- PMID:20376815
- PMID:20844343
- PMID:21343575
- PMID:21801220
- PMID:22436941
- PMID:23051063
- Patent:GB1003659
- Patent:US3340298
- Reaxys:2384653
- Wikipedia:Midodrine
- Ontology
- ChEBI ( EBI )
- Resources
- CTD
- is a type of
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- has_functional_parent
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- has_role
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- inverse is_conjugate_acid_of
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- is_conjugate_base_of
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Phenotype
Phenotype resulting from midodrine
Phenotype where environments contain midodrine
Phenotype modified by environments containing midodrine
Human Disease Model