Search Ontology:
ChEBI

latrunculin A

Term ID
CHEBI:69136
Synonyms
  • (+)-latrunculin A
  • (4R)-4-[(1R,4Z,8E,10Z,12S,15R,17R)-17-hydroxy-5,12-dimethyl-3-oxo-2,16-dioxabicyclo[13.3.1]nonadeca-4,8,10-trien-17-yl]-1,3-thiazolidin-2-one
  • LAT-A
  • LatA
  • LATRUNCULIN A
  • NSC 613011
Definition
A bicyclic macrolide natural product consisting of a 16-membered bicyclic lactone attached to the rare 2-thiazolidinone moiety. It is obtained from the Red Sea sponge Latrunculia magnifica and from the Fiji Islands sponge Cacospongia mycofijiensis. Latrunculin A inhibits actin polymerisation, microfilament organsation and microfilament-mediated processes.
References
Ontology
ChEBI  ( EBI )
Resources
CTD
Relationships
is a type of
has_role
Phenotype
Phenotype resulting from latrunculin A
Phenotype where environments contain latrunculin A
Phenotype modified by environments containing latrunculin A
Human Disease Model
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