ezogabine

Term ID

CHEBI:68584

Synonyms

D-23129
Ethyl 2-amino-4-((p-fluorobenzyl)amino)carbanilate
ethyl {2-amino-4-[(4-fluorobenzyl)amino]phenyl}carbamate
N-(2-Amino-4-(4-fluorobenzylamino)-phenyl) carbamic acid ethyl ester
N-(2-Amino-4-(4-fluorobenzylamino)phenyl)carbamic acid ethyl ester
Potiga
retigabine

Definition

A substituted aniline that is benzene-1,2,4-triamine bearing ethoxycarbonyl and 4-fluorobenzyl substituents at positions N-1 and N-4 respectively. An anticonvulsant used to treat seizures associated with epilepsy in adults.

References

CAS:150812-12-7
Drug_Central:4181
KEGG:C13826
KEGG:D09569
PMID:22991134
Patent:US2002015730
Patent:US2002111379
Patent:US2002183395
Patent:US2012053238
Patent:US5384330
Patent:US6348486
Patent:WO2007090409
Patent:WO2011012659
Reaxys:8072099
Wikipedia:Ezogabine

Ontology

ChEBI ( EBI )

Resources

CTD

Relationships

is a type of: carbamate ester organofluorine compound secondary amino compound substituted aniline

carbamate ester organofluorine compound secondary amino compound substituted aniline Show first 5 Terms
has_functional_parent: benzene-1,2,4-triamine

benzene-1,2,4-triamine Show first 5 Terms
has_role: anticonvulsant potassium channel modulator

anticonvulsant potassium channel modulator Show first 5 Terms

Phenotype

Phenotype resulting from ezogabine

Phenotype where environments contain ezogabine

Phenotype modified by environments containing ezogabine

Human Disease / Model Data