Search Ontology:
ChEBI
icatibant
- Term ID
- CHEBI:68556
- Synonyms
-
- (2S)-2-({[(2S,3aS,7aS)-1-({(3R)-2-[(2S)-2-{[(2S)-2-[2-({[(2S,4R)-1-({(2S)-1-[(2S)-2-{[(2R)-2-amino-5-carbamimidamidopentanoyl]amino}-5-carbamimidamidopentanoyl]pyrrolidin-2-yl}carbonyl)-4-hydroxypyrrolidin-2-yl]carbonyl}amino)acetamido]-3-(thiophen-2-yl)p
- D-arginyl-L-arginyl-L-prolyl-trans-4-hydroxy-L-prolylglycyl-3-(2-thienyl)-L-alanyl-L-seryl-D-1,2,3,4-tetrahydro-3-isoquinolinecarbonyl-L-(2alpha,3abeta,7abeta)-octahydro-1H-indole-2-carbonyl-L-arginine
- H-D-Arg-Arg-Pro-Hyp-Gly-Thi-Ser-D-Tic-Oic-Arg-OH
- icatibant
- icatibanto
- icatibantum
- Definition
- A ten-membered synthetic oligopeptide consisting of D-Arg, Arg, Pro, Hyp, Gly, Thi, Ser, D-Tic, Oic, and Arg residues joined in sequrence. A bradykinin receptor antagonist used as its acetate salt for the treatment of acute attacks of hereditary angioedema in adult patients.
- References
-
- CAS:130308-48-4
- DrugBank:DB06196
- PMID:21959973
- PMID:22142018
- PMID:22386830
- PMID:22434085
- PMID:22435954
- PMID:22507340
- PMID:22519593
- PMID:22522852
- PMID:22552531
- PMID:22577166
- PMID:22577920
- PMID:22584193
- PMID:22686628
- PMID:22691903
- PMID:22797560
- PMID:22830287
- PMID:22904641
- PMID:22936825
- PMID:22958093
- PMID:22970904
- Reaxys:8185933
- Wikipedia:Icatibant
- Ontology
- ChEBI ( EBI )
- Resources
- CTD
- is a type of
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- has_role
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- inverse has_part
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Phenotype
Phenotype resulting from icatibant
Phenotype where environments contain icatibant
Phenotype modified by environments containing icatibant
Human Disease / Model Data