azadiradione

Term ID

CHEBI:67280

Synonyms

(5alpha,7alpha,13alpha,17alpha)-17-(furan-3-yl)-4,4,8-trimethyl-3,16-dioxoandrosta-1,14-dien-7-yl acetate
24-Nor-5alpha,13alpha,17alpha-chola-1,14,20,22-tetraene-3,16-dione, 21,23-epoxy-7alpha-hydroxy-4,4,8-trimethyl-,acetate

Definition

A tetracyclic triterpenoid that is 4,4,8-trimethylandrosta-1,14-diene substituted by oxo groups at positions 3 and 16, an acetoxy group at position 7 and a furan-3-yl group at position 17. Isolated from Azadirachta indica, it exhibits antimycobacterial and anti-inflammatory activities.

References

Ontology

ChEBI ( EBI )

Relationships

is a type of: acetate ester cyclic terpene ketone furans limonoid tetracyclic triterpenoid

acetate ester cyclic terpene ketone furans limonoid tetracyclic triterpenoid Show first 5 Terms
has_role: anti-inflammatory agent antimycobacterial drug plant metabolite

anti-inflammatory agent antimycobacterial drug plant metabolite Show first 5 Terms
inverse has_functional_parent: 15-hydroxyazadiradione 17-hydroxyazadiradione desfuranoazadiradione epoxyazadiradione

15-hydroxyazadiradione 17-hydroxyazadiradione desfuranoazadiradione epoxyazadiradione Show first 5 Terms

Phenotype

Phenotype resulting from azadiradione

Phenotype where environments contain azadiradione

Phenotype modified by environments containing azadiradione

Human Disease / Model Data