megestrol acetate

Term ID

CHEBI:6723

Synonyms

• 17-acetoxy-6-methylpregna-4,6-diene-3,20-dione
• 17-hydroxy-6-methylpregna-4,6-diene-3,20-dione 17-acetate
• 17alpha-acetoxy-6-dehydro-6-methylprogesterone
• 17alpha-hydroxy-6-methylpregna-4,6-diene-3,20-dione acetate
• 6-dehydro-6-methyl-17alpha-acetoxyprogesterone
• 6-methyl-17alpha-acetoxypregna-4,6-diene-3,20-dione
• 6-methyl-17alpha-hydroxy-delta(sup 6)-progesterone acetate
• 6-methyl-3,20-dioxopregna-4,6-dien-17-yl acetate
• 6-methyl-6-dehydro-17alpha-acetoxyprogesterone
• 6-methyl-delta(sup 4,6)-pregnadien-17alpha-ol-3,20-dione acetate
• 6-methyl-delta(sup 6)-dehydro-17alpha-acetoxyprogesterone
• BDH 1298
• BDH-1298
• BDH1298
• magestin
• Maygace
• Megace
• Megeron
• Megestat
• Megestil
• Megestin
• Niagestin
• Ovaban
• Ovarid
• Pallace
• SC 10363
• SC-10363
• SC10363
• Volidan

Definition

A steroid ester resulting from the formal condensation of the hydroxy group of megestrol with the carboxy group of acetic acid. It is an appetite stimulant used for the treatment of anorexia and cachexia. Also used for birth control and for the treatment of breast cancer.

References

• Beilstein:1917291
• CAS:595-33-5
• DrugBank:DB00351
• KEGG:C08151
• KEGG:D00952
• LIPID_MAPS_instance:LMST02030118
• PMCID:PMC7207385
• PMID:11986264
• PMID:27038209
• PMID:27218795
• PMID:27639080
• PMID:28986550
• PMID:29050522
• PMID:29095656
• PMID:29400904
• PMID:29442239
• PMID:29542279
• PMID:29581752
• PMID:30112227
• PMID:30157059
• PMID:31036192
• PMID:31359357
• PMID:31451262
• PMID:31462353
• PMID:31497435
• PMID:31961463
• PMID:32084501
• PMID:32122805
• PMID:32652300
• PMID:5320316
• Patent:GB870286
• Patent:US2891079
• Patent:US3356573
• Patent:US3400137
• Wikipedia:Megestrol_acetate

Ontology

ChEBI  ( EBI )