7-oxo-3,8,9-trihydroxy staurosporine

Term ID

CHEBI:66839

Synonyms

(2S,3R,4R,6R)-11,22,23-trihydroxy-3-methoxy-2-methyl-4-(methylamino)-29-oxa-1,7,17-triazaoctacyclo[12.12.2.1[2,6].0[7,28].0[8,13].0[15,19].0[20,27].0[21,26]]nonacosa-8,10,12,14,19,21,23,25,27-nonaene- 16,18-dione
(5S,6R,7R,9R)-1,2,12-trihydroxy-6-methoxy-5-methyl-7-(methylamino)-6,7,8,9-tetrahydro-5H,14H-5,9-epoxy-4b,9a,15-triazadibenzo[b,h]cyclonona[1,2,3,4-jkl]cyclopenta[e]-as-indacene-14,16(15H)-dione

Definition

A indolocarbazole alkaloid that is staurosporine substituted by hydroxy groups at positions 3, 8 and 9 and an oxo group at position 7. Isolated from Cystodytes solitus, it exhibits cytotoxic activity.

References

PMID:18484775

Ontology

ChEBI ( EBI )

Relationships

is a type of: indolocarbazole indolocarbazole alkaloid organic heterooctacyclic compound polyphenol

indolocarbazole indolocarbazole alkaloid organic heterooctacyclic compound polyphenol Show first 5 Terms
has_functional_parent: staurosporine

staurosporine Show first 5 Terms
has_role: antineoplastic agent metabolite

antineoplastic agent metabolite Show first 5 Terms

Phenotype

Phenotype resulting from 7-oxo-3,8,9-trihydroxy staurosporine

Phenotype where environments contain 7-oxo-3,8,9-trihydroxy staurosporine

Phenotype modified by environments containing 7-oxo-3,8,9-trihydroxy staurosporine

Human Disease Model