orbiculin G

Term ID

CHEBI:66828

Synonyms

(3R,5S,5aR,6R,7S,9R,9aS,10R)-6-(acetyloxy)-2,2,5a,9-tetramethyloctahydro-2H-3,9a-methano-1-benzoxepine-5,7,10-triyl tribenzoate
1beta-acetoxy-2beta,6alpha,9alpha-tribenzoyloxy-dihydro-beta-agarofuran

Definition

A dihydroagarofuran sesquiterpenoid that consists of dihydro-beta-agarofuran substituted by an acetoxy group at position 1 and benzoyloxy groups at positions 2, 6 and 9 (the 1beta,2beta,6alpha,9alpha stereoisomers). Isolated from the roots of Celastrus orbiculatus and Microtropis fokienensis and exhibits cytotoxic and antitubercular properties.

References

PMID:10346948
PMID:17315960
Reaxys:8373955

Ontology

ChEBI ( EBI )

Relationships

is a type of: acetate ester benzoate ester bridged compound cyclic ether dihydroagarofuran sesquiterpenoid ... Show All 6 Terms

acetate ester benzoate ester bridged compound cyclic ether dihydroagarofuran sesquiterpenoid organic heterotricyclic compound Show first 5 Terms
has_role: antineoplastic agent antitubercular agent NF-kappaB inhibitor plant metabolite

antineoplastic agent antitubercular agent NF-kappaB inhibitor plant metabolite Show first 5 Terms
inverse has_functional_parent: 15-acetoxyorbiculin G

15-acetoxyorbiculin G Show first 5 Terms

Phenotype

Phenotype resulting from orbiculin G

Phenotype where environments contain orbiculin G

Phenotype modified by environments containing orbiculin G

Human Disease / Model Data