PF 1163A

Term ID

CHEBI:66740

Synonyms

(-)-PF 1163A
(3S,10R,13S)-3-[4-(2-hydroxyethoxy)benzyl]-13-[(2S)-2-hydroxypentyl]-4,10-dimethyl-1-oxa-4-azacyclotridecane-2,5-dione

Definition

A macrolide antibiotic that is 4,10-dimethyl-1-oxa-4-azacyclotridecane-2,5-dione substituted by a 4-(2-hydroxyethoxy)benzyl group at position 3 and a (2R)-2-hydroxypentyl group at position 13 (the 3S,10R,13S stereoisomer). It is isolated from Penicillium sp.PF1163 and exhibits antifungal activity against the pathogenic fungal strain Candida albicans TIMM1768.

References

Ontology

ChEBI ( EBI )

Relationships

is a type of: aromatic ether lactam macrolide antibiotic secondary alcohol

aromatic ether lactam macrolide antibiotic secondary alcohol Show first 5 Terms
has_role: antifungal agent Penicillium metabolite

antifungal agent Penicillium metabolite Show first 5 Terms

Phenotype

Phenotype resulting from PF 1163A

Phenotype where environments contain PF 1163A

Phenotype modified by environments containing PF 1163A

Human Disease Model