leachianone A

Term ID

CHEBI:66559

Synonyms

(2S)-5,7,4'-trihydroxy-8-lavandulyl-2'-methoxyflavanone
(2S)-5,7-dihydroxy-2-(4-hydroxy-2-methoxyphenyl)-8-[(2R)-5-methyl-2-(prop-1-en-2-yl)hex-4-en-1-yl]-2,3-dihydro-4H-chromen-4-one
(2S)-5,7-dihydroxy-2-(4-hydroxy-2-methoxyphenyl)-8-[(2R)-5-methyl-2-(prop-1-en-2-yl)hex-4-en-1-yl]-3,4-dihydro-2H-1-benzopyran-4-one

Definition

A trihydroxyflavanone that is (2S)-flavanone substituted by a lavandulyl group at position 8, hydroxy groups at positions 5, 7 and 4' and a methoxy group at position 2'. Isolated from the roots of Sophora flavescens and Sophora leachiana, it exhibits antineoplastic and antimalarial activity.

References

LIPID_MAPS_instance:LMPK12140468
PMID:10843587
Patent:KR20010084363
Reaxys:8594952

Ontology

ChEBI ( EBI )

Relationships

is a type of: 4'-hydroxyflavanones monomethoxyflavanone trihydroxyflavanone

4'-hydroxyflavanones monomethoxyflavanone trihydroxyflavanone Show first 5 Terms
has_functional_parent: (2S)-flavanone

(2S)-flavanone Show first 5 Terms
has_role: antimalarial antineoplastic agent metabolite

antimalarial antineoplastic agent metabolite Show first 5 Terms

Phenotype

Phenotype resulting from leachianone A

Phenotype where environments contain leachianone A

Phenotype modified by environments containing leachianone A

Human Disease Model