Search Ontology:
ChEBI
topopyrone B
- Term ID
- CHEBI:66253
- Synonyms
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- 8-chloro-5,7,9-trihydroxy-2-methyl-4H-naphtho[2,3-g]chromene-4,6,11-trione
- Definition
- A naphthochromene that is 4H-naphtho[2,3-g]chromene-4,6,11-trione substituted by a chloro group at position 8, hydroxy groups at positions 5, 7 and 9 and a methyl group at position 2. It is isolated from a fungal strain Phoma sp.BAUA2861 and acts as an inhibitor of the enzyme topoisomerase I.
- References
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- PMID:11099218
- PMID:11099219
- PMID:17020299
- Reaxys:8732205
- Ontology
- ChEBI ( EBI )
- is a type of
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- has_role
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Phenotype
Phenotype resulting from topopyrone B
Phenotype where environments contain topopyrone B
Phenotype modified by environments containing topopyrone B
Human Disease Model