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ChEBI

TMC-135B

Term ID
CHEBI:66233
Synonyms
  • (11E,13E,15E,21Z)-20,26-dihydroxy-10-methoxy-19,21-dimethyl-3,8-dioxo-3,4,7,8,9,10,17,18,19,20,23,24-dodecahydro-2H-25,6-(metheno)[1,4]thiazino[3,2-d]azacyclotricosin-18-yl 1-[(cyclohex-1-en-1-ylcarbonyl)amino]cyclopropanecarboxylate
  • (6E,8E,10E,16Z)-15,28-Dihydroxy-5-methoxy-14,16-dimethyl-3,24-dioxo-22-thia-2,25-diazatricyclo[18.7.1.0(21,26)]octacosa-1(28),6,8,10,16,20,26-heptaen-13-yl 1-[(1-cyclohexen-1-ylcarbonyl)amino]cyclopropanecarboxylate
Definition
An organonitrogen heterocyclic compound that is a 21-membered macrocyclic lactam substituted by a ({1-[(cyclohex-1-en-1-ylcarbonyl)amino]cyclopropyl}carbonyl)oxy group at position 18. It is isolated from Streptomyces sp. TC-1190 and exhibits growth inhibitory effects on a series of human tumour cell lines.
References
Ontology
ChEBI  ( EBI )
Relationships
is a type of
has_role
Phenotype
Phenotype resulting from TMC-135B
Phenotype where environments contain TMC-135B
Phenotype modified by environments containing TMC-135B
Human Disease / Model Data