4',5'-dihydro-11,5'-dihydroxy-4'-methoxytephrosin

Term ID

CHEBI:65772

Synonyms

(7aR,13aR)-2,6,7a-dihydroxy-1,9,10-trimethoxy-3,3-dimethyl-2,3,13,13a-tetrahydro-1H-chromeno[3,4-b]pyrano[2,3-h]chromen-7(7aH)-one

Definition

A member of the class of rotenones that is 4',5'-dihydrotephrosin substituted by hydroxy groups at positions 11 and 5' and a methoxy group at position 4'. It is isolated from the stems of Tephrosia toxicaria and exhibits antineoplastic activity.

References

Chemspider:9937202
PMID:14510590
Reaxys:9820416

Ontology

ChEBI ( EBI )

Relationships

is a type of: aromatic ether cyclic ketone organic heteropentacyclic compound rotenones secondary alcohol ... Show All 7 Terms

aromatic ether cyclic ketone organic heteropentacyclic compound rotenones secondary alcohol tertiary alcohol tertiary alpha-hydroxy ketone Show first 5 Terms
has_functional_parent: tephrosin

tephrosin Show first 5 Terms
has_role: antineoplastic agent metabolite

antineoplastic agent metabolite Show first 5 Terms

Phenotype

Phenotype resulting from 4',5'-dihydro-11,5'-dihydroxy-4'-methoxytephrosin

Phenotype where environments contain 4',5'-dihydro-11,5'-dihydroxy-4'-methoxytephrosin

Phenotype modified by environments containing 4',5'-dihydro-11,5'-dihydroxy-4'-methoxytephrosin

Human Disease Model