Search Ontology:
ChEBI
australifungin
- Term ID
- CHEBI:65459
- Synonyms
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- (4S,4aR,5S,7R,8R,8aS)-2,5,8-trihydroxy-4-[(2Z)-3-hydroxyprop-2-enoyl]-4,7-dimethyl-3-[(2R)-octan-2-yl]-4a,5,6,7,8,8a-hexahydronaphthalen-1(4H)-one
- Definition
- A carbobicyclic compound that is 4a,5,6,7,8,8a-hexahydronaphthalen-1(4H)-one substituted by hydroxy groups at positions 2, 5 and 8, a (2Z)-3-hydroxyprop-2-enoyl group at position 4, methyl groups at positions 4 and 7 and a 2R-octan-2-yl group at position 3 (the 4S,4aR,5S,7R,8R,8aS stereoisomer). It is isolated from the fermentation extracts of Sporormiella australis and exhibits antifungal activity by interfering with the fungal lipid metabolism.
- References
-
- PMID:10563338
- PMID:12684378
- PMID:18952903
- PMID:22226824
- PMID:7797434
- PMID:9516416
- Reaxys:7226637
- Ontology
- ChEBI ( EBI )
- is a type of
-
- has_role
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Phenotype
Phenotype resulting from australifungin
Phenotype where environments contain australifungin
Phenotype modified by environments containing australifungin
Human Disease Model