Search Ontology:
ChEBI

lomustine

Term ID
CHEBI:6520
Synonyms
  • 1-(2-chloroethyl)-3-cyclohexyl-1-nitrosourea
  • 1-(2-chloroethyl)-3-cyclohexylnitrosourea
  • Belustine
  • CCNU
  • Cecenu
  • CeeNU
  • chloroethylcyclohexylnitrosourea
  • CINU
  • cyclohexyl chloroethyl nitrosourea
  • lomustina
  • lomustine
  • lomustinum
  • N-(2-chloroethyl)-N'-cyclohexyl-N-nitrosourea
Definition
An N-nitrosourea that is urea in which one of the nitrogens is substituted by a 2-chloroethyl group and by a nitroso group, while the other nitrogen is substituted by a cyclohexyl group. An alkylating antineoplastic agent, it is used in the treatment of brain tumours, lung cancer, malignant melanoma and other solid tumours.
References
Ontology
ChEBI  ( EBI )
Resources
CTD
Relationships
is a type of
has_role
Phenotype
Phenotype resulting from lomustine
Phenotype where environments contain lomustine
Phenotype modified by environments containing lomustine
Human Disease / Model Data
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