Search Ontology:
ChEBI

lomustine

Term ID
CHEBI:6520
Synonyms
  • 1-(2-Chloroethyl)-3-cyclohexyl-1-nitrosourea
  • 1-(2-chloroethyl)-3-cyclohexylnitrosourea
  • Belustine
  • CCNU
  • Cecenu
  • CeeNU
  • chloroethylcyclohexylnitrosourea
  • CINU
  • cyclohexyl chloroethyl nitrosourea
  • lomustina
  • lomustine
  • lomustinum
  • N-(2-chloroethyl)-N'-cyclohexyl-N-nitrosourea
Definition
An N-nitrosourea that is urea in which one of the nitrogens is substituted by a 2-chloroethyl group and by a nitroso group, while the other nitrogen is substituted by a cyclohexyl group. An alkylating antineoplastic agent, it is used in the treatment of brain tumours, lung cancer, malignant melanoma and other solid tumours.
References
Ontology
ChEBI  ( EBI )
Resources
CTD
Relationships
is a type of
has_role
Phenotype
Phenotype resulting from lomustine
Phenotype where environments contain lomustine
Phenotype modified by environments containing lomustine
Human Disease Model
Your Input Welcome
We welcome your input and comments. Please use this form to recommend updates to the information in ZFIN. We appreciate as much detail as possible and references as appropriate. We will review your comments promptly.
Please check the highlighted fields and try again.
Thank you for submitting comments. Your input has been emailed to ZFIN curators who may contact you if additional information is required.
Oops. Something went wrong. Please try again later.