levamisole

Term ID

CHEBI:6432

Synonyms

• (-)-6-phenyl-2,3,5,6-tetrahydroimidazo[2,1-b][1,3]thiazole
• (-)-6-phenyl-2,3,5,6-tetrahydroimidazo[2,1-b]thiazole
• (-)-tetramisole
• (6S)-6-phenyl-2,3,5,6-tetrahydroimidazo[2,1-b][1,3]thiazole
• (S)-(-)-levamisole
• (S)-(-)-tetramisole
• (S)-2,3,5,6-tetrahydro-6-phenylimidazo[2,1-b]thiazole
• Ketrax
• Lepuron
• levamisol
• levamisole
• levamisolum
• Levomysol
• Levovermax
• Totalon
• Wormicid

Definition

A 6-phenyl-2,3,5,6-tetrahydroimidazo[2,1-b][1,3]thiazole that has S configuration. It is used (generally as the monohydrochloride salt) to treat parasitic worm infections in pigs, sheep and cattle and was formerly used in humans as an adjuvant to chemotherapy for the treatment of various cancers. It is also widely used as an adulterant to coccaine.

References

• CAS:14769-73-4
• DrugBank:DB00848
• Drug_Central:1561
• HMDB:HMDB0014986
• KEGG:C07070
• KEGG:D08114
• LINCS:LSM-6655
• PMID:10701095
• PMID:12232676
• PMID:12749943
• PMID:15109274
• PMID:1618599
• PMID:17608969
• PMID:189006
• PMID:2050823
• PMID:22337783
• PMID:22607692
• PMID:23041983
• PMID:23152411
• PMID:23543977
• PMID:23577329
• PMID:23649929
• PMID:23921349
• PMID:24365689
• PMID:24440755
• PMID:365327
• PMID:366135
• PMID:366137
• PMID:669135
• PMID:6995092
• PMID:6995094
• PMID:7051554
• PMID:827785
• Patent:US3274209
• Patent:US3565907
• Patent:US3579530
• Reaxys:4233256
• VSDB:1798
• Wikipedia:Levamisole

Ontology

ChEBI  ( EBI )

Resources

CTD