Search Ontology:
ChEBI
memantine
- Term ID
- CHEBI:64312
- Synonyms
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- 1,3-Dimethyl-5-adamantanamine
- 1-Amino-3,5-dimethyladamantane
- 3,5-Dimethyl-1-adamantanamine
- 3,5-Dimethyl-1-aminoadamantane
- 3,5-dimethyladamantan-1-amine
- 3,5-Dimethyltricyclo(3.3.1.1(3,7))decan-1-amine
- memantina
- memantine
- memantinum
- Definition
- A primary aliphatic amine that is the 3,5-dimethyl derivative of 1-aminoadamantane. A low to moderate affinity uncompetitive (open-channel); NMDA receptor antagonist which binds preferentially to the NMDA receptor-operated cation channels.
- References
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- CAS:19982-08-2
- DrugBank:DB01043
- Drug_Central:1679
- KEGG:C13736
- KEGG:D08174
- LINCS:LSM-5154
- PMID:20104942
- PMID:21953515
- PMID:21955815
- PMID:22030128
- PMID:22134197
- PMID:22245025
- PMID:22248638
- PMID:22290557
- PMID:22297273
- PMID:22300835
- PMID:22311362
- PMID:22327556
- PMID:22329473
- PMID:22392787
- PMID:22414570
- PMID:22425751
- Patent:US2011282100
- Reaxys:2075983
- Wikipedia:Memantine
- Ontology
- ChEBI ( EBI )
- Resources
- CTD
- is a type of
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- has_parent_hydride
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- has_role
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- inverse is_conjugate_acid_of
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- is_conjugate_base_of
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Phenotype
Phenotype resulting from memantine
Phenotype where environments contain memantine
Phenotype modified by environments containing memantine
Human Disease Model