(1S,2R)-5-methoxy-1-methyl-2-(propylamino)tetralin

Term ID

CHEBI:64117

Synonyms

(+)-AJ 76
(1S,2R)-5-methoxy-1-methyl-N-propyl-1,2,3,4-tetrahydronaphthalen-2-amine
5-Methoxy-1-methyl-2-(n-propylamino)tetralin
AJ 76
AJ-76
cis-(+)-5-methoxy-1-methyl-2-(propylamino)tetralin

Definition

A secondary amino compound that consists of tetralin bearing methyl, propylamino and methoxy groups at positions 1, 2 and 5 respectively. Dopamine receptor antagonist with preferential action at presynaptic receptors (pKi values are 6.95, 6.67, 6.37, 6.21 and 6.07 at hD3. hD4, hD2S, hD2L and rD2 receptors respectively).

References

Ontology

ChEBI ( EBI )

Resources

CTD

Relationships

is a type of: secondary amino compound tetralins

secondary amino compound tetralins Show first 5 Terms
has_parent_hydride: tetralin

tetralin Show first 5 Terms
has_role: dopaminergic antagonist

dopaminergic antagonist Show first 5 Terms
inverse is_conjugate_acid_of: (1S,2R)-5-methoxy-1-methyl-2-(propylammonio)tetralin(1+)

(1S,2R)-5-methoxy-1-methyl-2-(propylammonio)tetralin(1+) Show first 5 Terms
is_conjugate_base_of: (1S,2R)-5-methoxy-1-methyl-2-(propylammonio)tetralin(1+)

(1S,2R)-5-methoxy-1-methyl-2-(propylammonio)tetralin(1+) Show first 5 Terms

Phenotype

Phenotype resulting from (1S,2R)-5-methoxy-1-methyl-2-(propylamino)tetralin

Phenotype where environments contain (1S,2R)-5-methoxy-1-methyl-2-(propylamino)tetralin

Phenotype modified by environments containing (1S,2R)-5-methoxy-1-methyl-2-(propylamino)tetralin

Human Disease Model