sodium 8-bromo-3',5'-cyclic GMP

Term ID

CHEBI:64104

Synonyms

8-bromo cGMP sodium salt
8-bromoguanosine 3',5'-cyclic phosphate sodium
8-bromoguanosine 3',5'-cyclic phosphate sodium salt
sodium 8-bromoguanosine 3',5'-cyclic phosphate
sodium 8-bromoguanosine 3',5'-phosphate

Definition

An organic sodium salt having 8-bromoguanosine 3',5'-cyclic phosphate as the counterion. A membrane permeable cGMP analogue that activates protein kinase G (PKG). It is 4.3-fold more potent than cGMP in activating PKG1alpha and promotes relaxation of tracheal and vascular smooth muscle tissue in vitro.

References

Reaxys:8378760

Ontology

ChEBI ( EBI )

Relationships

is a type of: organic sodium salt

organic sodium salt Show first 5 Terms
has_part: 8-bromo-3',5'-cyclic GMP(1-)

8-bromo-3',5'-cyclic GMP(1-) Show first 5 Terms
has_role: muscle relaxant protein kinase G agonist

muscle relaxant protein kinase G agonist Show first 5 Terms

Phenotype

Phenotype resulting from sodium 8-bromo-3',5'-cyclic GMP

Phenotype where environments contain sodium 8-bromo-3',5'-cyclic GMP

Phenotype modified by environments containing sodium 8-bromo-3',5'-cyclic GMP

Human Disease Model