1-[2-(benzhydryloxy)ethyl]-4-(3-phenylpropyl)piperazine

Term ID

CHEBI:64093

Synonyms

1-[2-(diphenylmethoxy)ethyl]-4-(3-phenylpropyl)piperazine
Gbr 12935
GBR12935

Definition

An N-alkylpiperazine that consists of piperazine bearing 2-(benzhydryloxy)ethyl and 3-phenylpropyl groups at positions 1 and 4 respectively. Potent and selective inhibitor of dopamine uptake (KD = 5.5 nM in rat striatal membranes).

References

Ontology

ChEBI ( EBI )

Relationships

is a type of: ether N-alkylpiperazine tertiary amino compound

ether N-alkylpiperazine tertiary amino compound Show first 5 Terms
has_role: dopamine uptake inhibitor

dopamine uptake inhibitor Show first 5 Terms
inverse is_conjugate_acid_of: 1-[2-(benzhydryloxy)ethyl]-4-(3-phenylpropyl)piperazinediium(2+)

1-[2-(benzhydryloxy)ethyl]-4-(3-phenylpropyl)piperazinediium(2+) Show first 5 Terms
is_conjugate_base_of: 1-[2-(benzhydryloxy)ethyl]-4-(3-phenylpropyl)piperazinediium(2+)

1-[2-(benzhydryloxy)ethyl]-4-(3-phenylpropyl)piperazinediium(2+) Show first 5 Terms

Phenotype

Phenotype resulting from 1-[2-(benzhydryloxy)ethyl]-4-(3-phenylpropyl)piperazine

Phenotype where environments contain 1-[2-(benzhydryloxy)ethyl]-4-(3-phenylpropyl)piperazine

Phenotype modified by environments containing 1-[2-(benzhydryloxy)ethyl]-4-(3-phenylpropyl)piperazine

Human Disease Model