Search Ontology:
ChEBI
CGP 78608 hydrochloride
- Term ID
- CHEBI:64065
- Synonyms
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- (1S)-N-[(7-bromo-2,3-dioxo-1,2,3,4-tetrahydroquinoxalin-5-yl)methyl]-1-phosphonoethanaminium chloride
- [(1S)-1-{[(7-bromo-2,3-dioxo-1,2,3,4-tetrahydroquinoxalin-5-yl)methyl]amino}ethyl]phosphonic acid hydrochloride
- Definition
- A hydrochloride that is the monohydrochloride salt of CGP 78608. Potent and selective NMDA antagonist that acts through the glycine site (IC50 = 5 nM). Displays >500-fold selectivity over kainate and AMPA receptors (IC50 values are 2.7 and 3 muM respectively). Anticonvulsant in vivo following systemic administration.
- References
- Ontology
- ChEBI ( EBI )
- is a type of
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- has_role
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- inverse is_conjugate_acid_of
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- is_conjugate_base_of
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Phenotype
Phenotype resulting from CGP 78608 hydrochloride
Phenotype where environments contain CGP 78608 hydrochloride
Phenotype modified by environments containing CGP 78608 hydrochloride
Human Disease / Model Data