3-[4-(3-chlorophenyl)piperazin-1-yl]-1,1-diphenylpropan-2-ol

Term ID

CHEBI:64060

Synonyms

1-(diphenylmethyl)-2-(4-(3-chlorophenyl)-1-piperazinyl)ethanol
3-(4-(3-chlorophenyl)-1-piperazinyl)-1,1-diphenyl-2-propanol
3-(4-(3-chlorophenyl)piperazin-1-yl)-1,1,-diphenyl-2-propanol
3-[4-(3-chlorophenyl)piperazin-1-yl]-1,1-diphenylpropan-2-ol
BRL 15572
BRL-15,572
BRL-15572
BRL15572

Definition

An N-alkylpiperazine that is 1-(3-chlorophenyl)piperazine carrying a 3,3-diphenyl-2-hydroxyprop-1-yl group at position 4. A selective h5-HT1D antagonist, displaying 60-fold selectivity over h5-HT1B, and exhibiting little or no affinity for a range of other receptor types.

References

Ontology

ChEBI ( EBI )

Relationships

is a type of: monochlorobenzenes N-alkylpiperazine N-arylpiperazine secondary alcohol

monochlorobenzenes N-alkylpiperazine N-arylpiperazine secondary alcohol Show first 5 Terms
has_role: geroprotector serotonergic antagonist

geroprotector serotonergic antagonist Show first 5 Terms
inverse is_conjugate_acid_of: 4-(3-chlorophenyl)-1-(2-hydroxy-3,3-diphenylpropyl)piperazin-1-ium(1+)

4-(3-chlorophenyl)-1-(2-hydroxy-3,3-diphenylpropyl)piperazin-1-ium(1+) Show first 5 Terms
is_conjugate_base_of: 4-(3-chlorophenyl)-1-(2-hydroxy-3,3-diphenylpropyl)piperazin-1-ium(1+)

4-(3-chlorophenyl)-1-(2-hydroxy-3,3-diphenylpropyl)piperazin-1-ium(1+) Show first 5 Terms

Phenotype

Phenotype resulting from 3-[4-(3-chlorophenyl)piperazin-1-yl]-1,1-diphenylpropan-2-ol

Phenotype where environments contain 3-[4-(3-chlorophenyl)piperazin-1-yl]-1,1-diphenylpropan-2-ol

Phenotype modified by environments containing 3-[4-(3-chlorophenyl)piperazin-1-yl]-1,1-diphenylpropan-2-ol

Human Disease / Model Data