Search Ontology:
ChEBI
4-(4-methylpiperazin-1-yl)-7-(trifluoromethyl)pyrrolo[1,2-a]quinoxaline
- Term ID
- CHEBI:64055
- Synonyms
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- 4-(4-methylpiperazin-1-yl)-7-(trifluoromethyl)pyrrolo[1,2-a]quinoxaline
- CGS 12066B
- Definition
- A pyrroloquinoxaline that is pyrrolo[1,2-a]quinoxaline bearing additional 4-methylpiperazin-1-yl and trifluoromethyl substituents at positions 4 and 7 respectively. A 5-hydroxytryptamine receptor 1B (5-HT1B) full agonist, 10-fold selective over 5-HT1A and 1000-fold selective over 5-HT2C receptors. Centrally active following systemic administration.
- References
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- LINCS:LSM-2420
- PMID:10607113
- PMID:11224163
- PMID:11224442
- PMID:1362158
- PMID:1645675
- PMID:17392733
- PMID:2255331
- PMID:3496228
- PMID:7501681
- PMID:8223931
- Reaxys:4206934
- Ontology
- ChEBI ( EBI )
- is a type of
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- has_role
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- inverse has_part
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Phenotype
Phenotype resulting from 4-(4-methylpiperazin-1-yl)-7-(trifluoromethyl)pyrrolo[1,2-a]quinoxaline
Phenotype where environments contain 4-(4-methylpiperazin-1-yl)-7-(trifluoromethyl)pyrrolo[1,2-a]quinoxaline
Phenotype modified by environments containing 4-(4-methylpiperazin-1-yl)-7-(trifluoromethyl)pyrrolo[1,2-a]quinoxaline
Human Disease / Model Data