latanoprost free acid

Term ID

CHEBI:63925

Synonyms

• (5Z)-7-{(1R,2R,3R,5S)-3,5-dihydroxy-2-[(3R)-3-hydroxy-5-phenylpentyl]cyclopentyl}hept-5-enoic acid
• 13,14-dihydro-17-phenyl-18,19,20-trinor-PGF2alpha
• latanoprost acid
• Phxa 85

Definition

A prostaglandin Falpha that is an analogue of prostaglandin F2alpha in which the pentyl group has been replaced by 2-phenylethyl and where the the 13,14-double bond has undergone formal hydrogenation. Its isopropyl ester prodrug, latanoprost, is used in the treatment of open-angle glaucoma and ocular hypertension.

References

• CAS:41639-83-2
• PMID:18451496
• PMID:19084521
• PMID:19289115
• PMID:20019365
• PMID:21396362
• PMID:21788077
• PMID:21791206
• PMID:22124989
• PMID:22136089
• Reaxys:5911495

Ontology

ChEBI  ( EBI )

Resources

CTD