Search Ontology:
ChEBI
pemetrexed disodium
- Term ID
- CHEBI:63722
- Synonyms
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- disodium (2S)-2-({4-[2-(2-amino-4-oxo-4,7-dihydro-1H-pyrrolo[2,3-d]pyrimidin-5-yl)ethyl]benzoyl}amino)pentanedioate
- disodium N-{4-[2-(2-amino-4-oxo-4,7-dihydro-1H-pyrrolo[2,3-d]pyrimidin-5-yl)ethyl]benzoyl}-L-glutamate
- Definition
- An organic sodium salt that is the disodium salt of N-{4-[2-(2-amino-4-oxo-4,7-dihydro-1H-pyrrolo[2,3-d]pyrimidin-5-yl)ethyl]benzoyl}-L-glutamic acid. Inhibits thymidylate synthase (TS), 421 dihydrofolate reductase (DHFR), and glycinamide ribonucleotide formyltransferase (GARFT).
- References
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- CAS:150399-23-8
- DrugBank:DB00642
- KEGG:D03828
- PMID:19137122
- PMID:20209614
- Patent:CN101411710
- Patent:CN101560206
- Patent:EP2301909
- Patent:EP2334685
- Patent:US2009181990
- Patent:US2011124861
- Patent:US2011196154
- Patent:WO2010028105
- Patent:WO2011019986
- Patent:WO2011064256
- Reaxys:8964395
- Ontology
- ChEBI ( EBI )
- is a type of
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- has_part
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- has_role
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- inverse has_part
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Phenotype
Phenotype resulting from pemetrexed disodium
Phenotype where environments contain pemetrexed disodium
Phenotype modified by environments containing pemetrexed disodium
Human Disease Model