(-)-(11S,2'R)-erythro-mefloquine

Term ID

CHEBI:63687

Synonyms

(-)-Mefloquine
(S)-[2,8-bis(trifluoromethyl)quinolin-4-yl][(2R)-piperidin-2-yl]methanol
[(11S,2'R)-2,8-bis(trifluoromethyl)quinolin-4-yl]-(2-piperidyl)methanol

Definition

An optically active form of [2,8-bis(trifluoromethyl)quinolin-4-yl]-(2-piperidyl)methanol having (-)-(11S,2'R)-erythro-configuration. An antimalarial agent, used in racemic form, which acts as a blood schizonticide; its mechanism of action is unknown.

References

CAS:51742-87-1
LINCS:LSM-5525
Reaxys:5629059

Ontology

ChEBI ( EBI )

Relationships

is a type of: [2,8-bis(trifluoromethyl)quinolin-4-yl]-(2-piperidyl)methanol

[2,8-bis(trifluoromethyl)quinolin-4-yl]-(2-piperidyl)methanol Show first 5 Terms
has_role: antimalarial

antimalarial Show first 5 Terms
inverse has_part: mefloquine

mefloquine Show first 5 Terms
inverse is_enantiomer_of: (+)-(11R,2'S)-erythro-mefloquine

(+)-(11R,2'S)-erythro-mefloquine Show first 5 Terms
is_enantiomer_of: (+)-(11R,2'S)-erythro-mefloquine

(+)-(11R,2'S)-erythro-mefloquine Show first 5 Terms

Phenotype

Phenotype resulting from (-)-(11S,2'R)-erythro-mefloquine

Phenotype where environments contain (-)-(11S,2'R)-erythro-mefloquine

Phenotype modified by environments containing (-)-(11S,2'R)-erythro-mefloquine

Human Disease Model