Search Ontology:
ChEBI
valdecoxib
- Term ID
- CHEBI:63634
- Synonyms
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- 4-(5-methyl-3-phenyl-1,2-oxazol-4-yl)benzenesulfonamide
- 4-(5-Methyl-3-phenyl-4-isoxazolyl)benzenesulfonamide
- Bextra
- p-(5-Methyl-3-phenyl-4-isoxazolyl)benzenesulfonamide
- valdecoxib
- valdecoxibum
- Definition
- A member of the class of isoxazoles that is isoxazole which is substituted at positions 3, 4 and 5 by phenyl, p-sulfamoylphenyl and methyl groups, respectively. A selective cyclooxygenase 2-inhibitor, it used as a nonsteroidal anti-inflammatory drug (NSAID) for the treatment of arthritis from 2001 until 2005, when it was withdrawn following concerns of an associated increased risk of heart attack and stroke.
- References
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- CAS:181695-72-7
- DrugBank:DB00580
- Drug_Central:2799
- HMDB:HMDB0005033
- KEGG:D02709
- LINCS:LSM-5305
- PDBeChem:COX
- PMID:20467258
- PMID:20717044
- PMID:21073910
- PMID:21720517
- PMID:21769548
- Reaxys:8563786
- Wikipedia:Valdecoxib
- Ontology
- ChEBI ( EBI )
- is a type of
-
- has_role
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- inverse has_functional_parent
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Phenotype
Phenotype resulting from valdecoxib
Phenotype where environments contain valdecoxib
Phenotype modified by environments containing valdecoxib
Human Disease / Model Data