Search Ontology:
ChEBI
N-Ac-Asp-N(6)-lipoyl-KATIGFEVQEE
- Term ID
- CHEBI:60738
- Synonyms
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- lipoated PDC-E2 173-184 peptide
- N-Ac-Asp-N(6)-{(R)-lipoyl}-KATIGFEVQEE
- N-Ac-Asp-N(6)-{5-[(3R)-1,2-dithiolan-3-yl]pentanoyl}-Lys-Ala-Thr-Ile-Gly-Phe-Glu-Val-Gln-Glu-Glu
- N-acetyl-L-alpha-aspartyl-N(6)-{5-[(3R)-1,2-dithiolan-3-yl]pentanoyl}-L-lysyl-L-alanyl-L-threonyl-L-isoleucylglycyl-L-phenylalanyl-L-alpha-glutamyl-L-valyl-L-glutaminyl-L-alpha-glutamyl-L-glutamic acid
- Definition
- A polypeptide comprising the 12-amino acid sequence KATIGFEVQEE where the N-terminal lysyl (K) residue has an acetyl group at the Nalpha-position and a lipoyl group on the side-chain. A component of the inner lipoyl domain of the second enzyme of the pyruvate dehydrogenase complex (PDC-E2), to which antibodies are raised in the autoimmune disease primary biliary cirrhosis.
- References
- Ontology
- ChEBI ( EBI )
- is a type of
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- has_role
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Phenotype
Phenotype resulting from N-Ac-Asp-N(6)-lipoyl-KATIGFEVQEE
Phenotype where environments contain N-Ac-Asp-N(6)-lipoyl-KATIGFEVQEE
Phenotype modified by environments containing N-Ac-Asp-N(6)-lipoyl-KATIGFEVQEE
Human Disease / Model Data