(S)-etodolac

Term ID

CHEBI:60371

Synonyms

(+)-[1,8-diethyl-1,3,4,9-tetrahydropyrano[3,4-b]indol-1-yl]acetic acid
(+)-etodolac
(S)-(+)-etodolac
[(1S)-1,8-diethyl-1,3,4,9-tetrahydropyrano[3,4-b]indol-1-yl]acetic acid

Definition

The S-enantiomer of etodolac. It is a preferential inhibitor of cyclo-oxygenase 2 and a non-steroidal anti-inflammatory, whereas the enantiomer, (R)-etodolac, is inactive. The racemate is commonly used for the treatment of rheumatoid arthritis and osteoarthritis, and for the alleviation of postoperative pain.

References

Ontology

ChEBI ( EBI )

Relationships

is a type of: etodolac

etodolac Show first 5 Terms
has_role: cyclooxygenase 2 inhibitor non-narcotic analgesic

cyclooxygenase 2 inhibitor non-narcotic analgesic Show first 5 Terms
inverse is_enantiomer_of: (R)-etodolac

(R)-etodolac Show first 5 Terms
is_enantiomer_of: (R)-etodolac

(R)-etodolac Show first 5 Terms

Phenotype

Phenotype resulting from (S)-etodolac

Phenotype where environments contain (S)-etodolac

Phenotype modified by environments containing (S)-etodolac

Human Disease Model