Search Ontology:
ChEBI

amorolfine

Term ID
CHEBI:599440
Synonyms
  • (+-)-cis-2,6-dimethyl-4-(2-methyl-3-(p-tert-pentylphenyl)propyl)morpholine
  • (2R,6S)-2,6-dimethyl-4-{2-methyl-3-[4-(2-methylbutan-2-yl)phenyl]propyl}morpholine
  • amorolfina
  • amorolfine
  • amorolfinum
  • meso-2,6-dimethyl-4-(2-methyl-3-(p-tert-pentylphenyl)propyl)morpholine
  • meso-2,6-dimethyl-4-{2-methyl-3-[4-(2-methylbutan-2-yl)phenyl]propyl}morpholine
Definition
A member of the class of morpholines that is cis-2,6-dimethylmorpholine in which the hydrogen attached to the nitrogen is replaced by a racemic 2-methyl-3-[p-(2-methylbutan-2-yl)phenyl]propyl group. An inhibitor of the action of squalene monooxygenase, Delta(14) reductase and D7-D8 isomerase and an antifungal agent, it is used (generally as its hydrochloride salt) for the topical treatment of fungal nail and skin infections.
References
Ontology
ChEBI  ( EBI )
Relationships
is a type of
has_role
inverse is_conjugate_base_of
is_conjugate_acid_of
Phenotype
Phenotype resulting from amorolfine
Phenotype where environments contain amorolfine
Phenotype modified by environments containing amorolfine
Human Disease / Model Data