diphemanil methylsulfate

Term ID

CHEBI:59782

Synonyms

• 4-(diphenylmethylene)-1,1-dimethylpiperidinium methyl sulfate
• 4-(diphenylmethylidene)-1,1-dimethylpiperidinium methyl sulfate
• diphemanil methosulfate
• diphemanil methylsulfate
• diphemanil metilsulfate
• diphemanili metilsulfas
• metilsulfate de diphemanil
• metilsulfato de difemanilo
• N,N-dimethyl-4-piperidylidene-1,1-diphenylmethane methylsulfate
• p-(alpha-phenylbenzylidene)-1,1-dimethylpiperidinium methyl sulfate

Definition

The alkene resulting from the formal Wittig olefination of benzophenone and 1,1-dimethyl-4-bromopiperidinium methylsulfate. A quaternary ammonium anticholinergic, it binds muscarinic acetycholine receptors and thereby decreases secretory excretion of stomach acids, saliva and sweat, It is used topically in the treatment of hyperhidorsis (excessive sweating).

References

• Beilstein:3842254
• CAS:62-97-5
• DrugBank:DB00729
• KEGG:D06878
• Patent:US2739968
• Wikipedia:Diphemanil

Ontology

ChEBI  ( EBI )

Resources

CTD