Search Ontology:
ChEBI
bivalirudin
- Term ID
- CHEBI:59173
- Synonyms
-
- (2S)-2-[[(2S)-2-[[(2S)-2-[[(2S)-2-[[(2S)-1-[(2S,3S)-2-[[(2S)-2-[[(2S)-2-[[(2S)-2-[[(2S)-2-[[2-[[(2S)-4-amino-2-[[2-[[2-[[2-[[2-[[(2S)-1-[(2S)-2-[[(2S)-1-[(2R)-2-amino-3-cyclohexylpropanoyl]pyrrolidine-2-carbonyl]amino]-5-carbamimidamidopentanoyl]pyrrolidi
- bivalirudin
- bivalirudina
- bivalirudine
- bivalirudinum
- D-phenylalanyl-L-prolyl-L-arginyl-L-prolylglycylglycylglycylglycyl-L-asparaginylglycyl-L-alpha-aspartyl-L-phenylalanyl-L-alpha-glutamyl-L-alpha-glutamyl-L-isoleucyl-L-prolyl-L-alpha-glutamyl-L-alpha-glutamyl-L-tyrosyl-L-leucine
- Definition
- A synthetic peptide of 20 amino acids, comprising D-Phe, Pro, Arg, Pro, Gly, Gly, Gly, Gly, Asn, Gly, Asp, Phe, Glu, Glu, Ile, Pro, Glu, Glu, Tyr, and Leu in sequence. A congener of hirudin (a naturally occurring drug found in the saliva of the medicinal leech), it a specific and reversible inhibitor of thrombin, and is used as an anticoagulant.
- References
-
- Beilstein:12004535
- CAS:128270-60-0
- DrugBank:DB00006
- Drug_Central:385
- PMID:28844201
- PMID:29086730
- PMID:29276283
- PMID:29342377
- PMID:29345439
- PMID:29345440
- PMID:29345441
- PMID:29345444
- PMID:29350380
- PMID:29377655
- PMID:29461391
- PMID:29477790
- PMID:29544607
- PMID:29563377
- PMID:29600024
- Patent:WO9102750
- Ontology
- ChEBI ( EBI )
- Resources
- CTD
- is a type of
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- has_role
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Phenotype
Phenotype resulting from bivalirudin
Phenotype where environments contain bivalirudin
Phenotype modified by environments containing bivalirudin
Human Disease Model