(3S,5R)-fluvastatin

Term ID

CHEBI:5136

Synonyms

(-)-(3S,5R)-fluvastatin
(3S,5R)-(-)-fluvastatin
(3S,5R,6E)-7-[3-(4-fluorophenyl)-1-(propan-2-yl)-1H-indol-2-yl]-3,5-dihydroxyhept-6-enoic acid
(3S,5R,6E)-7-[3-(4-fluorophenyl)-1-isopropyl-1H-indol-2-yl]-3,5-dihydroxyhept-6-enoic acid

Definition

A (6E)-7-[3-(4-fluorophenyl)-1-(propan-2-yl)-1H-indol-2-yl]-3,5-dihydroxyhept-6-enoic acid diastereoisomer in which the stereocentres beta- and delta- to the carboxy group have S and R configuration, respectively. The drug fluvastatin is an equimolar mixture of this compound and its enantiomer.

References

KEGG:D07983
PMID:11817313
PMID:12489926
PMID:12891229
PMID:16480934
Reaxys:8169391

Ontology

ChEBI ( EBI )

Relationships

is a type of: (6E)-7-[3-(4-fluorophenyl)-1-(propan-2-yl)-1H-indol-2-yl]-3,5-dihydroxyhept-6-enoic acid statin (synthetic)

(6E)-7-[3-(4-fluorophenyl)-1-(propan-2-yl)-1H-indol-2-yl]-3,5-dihydroxyhept-6-enoic acid statin (synthetic) Show first 5 Terms
inverse has_part: fluvastatin

fluvastatin Show first 5 Terms
inverse is_conjugate_base_of: (3S,5R)-fluvastatin(1-)

(3S,5R)-fluvastatin(1-) Show first 5 Terms
inverse is_enantiomer_of: (3R,5S)-fluvastatin

(3R,5S)-fluvastatin Show first 5 Terms
is_conjugate_acid_of: (3S,5R)-fluvastatin(1-)

(3S,5R)-fluvastatin(1-) Show first 5 Terms
is_enantiomer_of: (3R,5S)-fluvastatin

(3R,5S)-fluvastatin Show first 5 Terms

Phenotype

Phenotype resulting from (3S,5R)-fluvastatin

Phenotype where environments contain (3S,5R)-fluvastatin

Phenotype modified by environments containing (3S,5R)-fluvastatin

Human Disease Model