Search Ontology:
ChEBI
EC 5.99.1.3 [DNA topoisomerase (ATP-hydrolysing)] inhibitor
- Term ID
- CHEBI:50750
- Synonyms
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- DNA gyrase inhibitor
- DNA gyrase inhibitors
- DNA topoisomerase (ATP-hydrolysing) (EC 5.99.1.3) inhibitor
- Definition
- A topoisomerase inhibitor that inhibits DNA topoisomerase (ATP-hydrolysing), EC 5.99.1.3 (also known as topoisomerase II and as DNA gyrase), which catalyses ATP-dependent breakage of both strands of DNA, passage of the unbroken strands through the breaks, and rejoining of the broken strands.
- References
- Ontology
- ChEBI ( EBI )
- is a type of
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- inverse has_role
Phenotype
Phenotype resulting from EC 5.99.1.3 [DNA topoisomerase (ATP-hydrolysing)] inhibitor
Phenotype where environments contain EC 5.99.1.3 [DNA topoisomerase (ATP-hydrolysing)] inhibitor
Phenotype modified by environments containing EC 5.99.1.3 [DNA topoisomerase (ATP-hydrolysing)] inhibitor
Human Disease Model