Search Ontology:
ChEBI
mercaptopurine
- Term ID
- CHEBI:50667
- Synonyms
-
- 1,7-dihydro-6H-purine-6-thione
- 6 MP
- 6-Mercaptopurine
- 6-MP
- 6-Thiohypoxanthine
- 6-Thioxopurine
- Mercaptopurina
- mercaptopurine
- mercaptopurinum
- Mercapurin
- Puri-Nethol
- Purinethol
- Definition
- A member of the class of purines that is 6,7-dihydro-1H-purine carrying a thione group at position 6. An adenine analogue, it is used in the treatment of acute lymphocytic leukemia (ALL), chronic myeloid leukemia (CML), Crohn's disease, and ulcerative colitis.
- References
-
- Beilstein:132916
- CAS:50-44-2
- DrugBank:DB01033
- KEGG:C02380
- KEGG:D04931
- PDBeChem:PM6
- PMID:16267626
- PMID:28011186
- PMID:28166217
- PMID:28212467
- PMID:28295989
- PMID:28301625
- PMID:28406092
- PMID:28418010
- PMID:28484608
- PMID:28574837
- Patent:US2697709
- Patent:US2721866
- Reaxys:132916
- Ontology
- ChEBI ( EBI )
- is a type of
-
- has_role
-
- inverse has_part
-
- inverse is_tautomer_of
-
- is_tautomer_of
-
Phenotype
Phenotype resulting from mercaptopurine
Phenotype where environments contain mercaptopurine
Phenotype modified by environments containing mercaptopurine
Human Disease Model