Search Ontology:
ChEBI
nitisinone
- Term ID
- CHEBI:50378
- Synonyms
-
- 2-(alpha,alpha,alpha-Trifluoro-2-nitro-p-tuluoyl)-1,3-cyclohexanedione
- 2-[2-nitro-4-(trifluoromethyl)benzoyl]cyclohexane-1,3-dione
- nitisinona
- nitisinone
- nitisinonum
- Orfadin
- Definition
- A cyclohexanone that is cyclohexane-1,3-dione substituted at position 2 by a 2-nitro-4-(trifluoromethyl)benzoyl group. It is used in the treatment of hereditary tyrosinemia type 1.
- References
-
- CAS:104206-65-7
- DrugBank:DB00348
- Drug_Central:1944
- HMDB:HMDB0014492
- KEGG:D05177
- PMID:14668946
- PMID:15297036
- PMID:17152330
- PMID:17458044
- PMID:20883679
- PMID:21377430
- PMID:21620748
- PMID:21752152
- PMID:21813063
- PMID:21968107
- PMID:21968110
- PMID:22456946
- PMID:22885033
- PMID:23146787
- PMID:23203167
- PMID:23250512
- PMID:23311542
- PMID:23430914
- PMID:23430917
- PMID:23486607
- PMID:23511227
- Patent:EP186118
- Patent:US4774360
- Patent:US5006158
- Patent:US5550165
- Patent:US5668089
- Reaxys:8639943
- Wikipedia:Nitisinone
- Ontology
- ChEBI ( EBI )
- is a type of
-
- has_role
-
Phenotype
Phenotype resulting from nitisinone
Phenotype where environments contain nitisinone
Phenotype modified by environments containing nitisinone
Human Disease / Model Data