Search Ontology:
ChEBI
edrophonium chloride
- Term ID
- CHEBI:4759
- Synonyms
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- (3-hydroxyphenyl)dimethylethylammonium chloride
- 3-hydroxy-N,N-dimethyl-N-ethylanilinium chloride
- chlorure d'edrophonium
- cloruro de edrofonio
- edrophonii chloridum
- EDROPHONIUM CHLORIDE
- ethyl(m-hydroxyphenyl)dimethylammonium chloride
- N-ethyl-3-hydroxy-N,N-dimethylanilinium chloride
- N-ethyl-3-hydroxy-N,N-dimethylbenzenaminium chloride
- Definition
- The chloride salt of edrophonium. A reversible inhibitor of cholinesterase with a rapid onset (30-60 seconds after injection) but a short duration of action (5-15 minutes), it is used in myasthenia gravis both diagnostically and to distinguish between under- or over-treatment with other anticholinesterases. It has also been used for the reversal of neuromuscular blockade in anaesthesia, and for the management of poisoning due to tetrodotoxin, a neuromuscular blocking toxin found in puffer fish and other marine animals.
- References
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- Beilstein:3748734
- CAS:116-38-1
- DrugBank:DB01010
- KEGG:D00994
- PMID:7488499
- Patent:US2647924
- Wikipedia:Edrophonium
- Ontology
- ChEBI ( EBI )
- is a type of
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- has_part
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- has_role
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Show first 5 Terms
Phenotype
Phenotype resulting from edrophonium chloride
Phenotype where environments contain edrophonium chloride
Phenotype modified by environments containing edrophonium chloride
Human Disease / Model Data