N-[2-(4-bromocinnamylamino)ethyl]isoquinoline-5-sulfonamide

Term ID

CHEBI:47495

Synonyms

H 89
H-89
H89
N-(2-{[3-(4-bromophenyl)prop-2-en-1-yl]amino}ethyl)isoquinoline-5-sulfonamide
N-[2-(4-bromocinnamylamino)ethyl]-5-isoquinoline sulfonamide
N-[2-[[3-(4-bromophenyl)-2-propen-1-yl]amino]ethyl]-5-isoquinolinesulfonamide
protein kinase inhibitor H89

(all 7)

Definition

A member of the class of isoquinolines that is the sulfonamide obtained by formal condensation of the sulfo group of isoquinoline-5-sulfonic acid with the primary amino group of N(1)-[3-(4-bromophenyl)prop-2-en-1-yl]ethane-1,2-diamine. It is a protein kinase A inhibitor.

References

(all 18)

Ontology

ChEBI ( EBI )

Resources

CTD

Relationships

is a type of: bromobenzenes isoquinolines olefinic compound secondary amino compound sulfonamide

bromobenzenes isoquinolines olefinic compound secondary amino compound sulfonamide Show first 5 Terms
has subtype: (E)-N-[2-(4-bromocinnamylamino)ethyl]isoquinoline-5-sulfonamide

(E)-N-[2-(4-bromocinnamylamino)ethyl]isoquinoline-5-sulfonamide Show first 5 Terms
has_role: EC 2.7.11.11 (cAMP-dependent protein kinase) inhibitor

EC 2.7.11.11 (cAMP-dependent protein kinase) inhibitor Show first 5 Terms
inverse is_conjugate_acid_of: N-[2-(4-bromocinnamylamino)ethyl]isoquinoline-5-sulfonamide(2+)

N-[2-(4-bromocinnamylamino)ethyl]isoquinoline-5-sulfonamide(2+) Show first 5 Terms
is_conjugate_base_of: N-[2-(4-bromocinnamylamino)ethyl]isoquinoline-5-sulfonamide(2+)

N-[2-(4-bromocinnamylamino)ethyl]isoquinoline-5-sulfonamide(2+) Show first 5 Terms

Phenotype

Phenotype resulting from N-[2-(4-bromocinnamylamino)ethyl]isoquinoline-5-sulfonamide

Phenotype where environments contain N-[2-(4-bromocinnamylamino)ethyl]isoquinoline-5-sulfonamide

Phenotype modified by environments containing N-[2-(4-bromocinnamylamino)ethyl]isoquinoline-5-sulfonamide

Human Disease Model