Search Ontology:
ChEBI
doxercalciferol
- Term ID
- CHEBI:4712
- Synonyms
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- (1S,3R,5Z,7E,22E)-9,10-secoergosta-5,7,10,22-tetraene-1,3-diol
- 1alpha-hydroxyergocalciferol
- 1alpha-hydroxyvitamin D2
- doxercalciferol
- doxercalciferolum
- Hectorol
- Definition
- A hydroxy seco-steroid and synthetic vitamin D2 analogue that undergoes metabolic activation in vivo to form 1alpha,25-dihydroxyvitamin D2 (1alpha,25-(OH)2D2), a naturally occurring, biologically active form of vitamin D2. It is used to treat secondary hyperparathyroidism, a condition in which the body produces excess parathyroid hormone (PTH; a natural substance needed to control the amount of calcium in the blood) in certain people with chronic kidney disease.
- References
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- CAS:54573-75-0
- DrugBank:DB06410
- Drug_Central:957
- KEGG:C08211
- KEGG:D01009
- PDBeChem:V2H
- PMID:12227689
- PMID:12834181
- PMID:17603751
- PMID:21155068
- PMID:21849802
- PMID:22123370
- PMID:23780943
- PMID:25774916
- PMID:28586017
- Wikipedia:Doxercalciferol
- Ontology
- ChEBI ( EBI )
- is a type of
-
- has_role
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Phenotype
Phenotype resulting from doxercalciferol
Phenotype where environments contain doxercalciferol
Phenotype modified by environments containing doxercalciferol
Human Disease Model