Search Ontology:
ChEBI
(-)-demecolcine
- Term ID
- CHEBI:4393
- Synonyms
-
- (-)-colchamine
- (7S)-1,2,3,10-tetramethoxy-7-(methylamino)-6,7-dihydrobenzo[a]heptalen-9(5H)-one
- Colcemid
- demecolcina
- demecolcine
- demecolcinum
- N-deacetyl-N-methylcolchicine
- N-desacetyl-N-methylcolchicine
- N-methyl-N-deacetylcolchicine
- N-methyl-N-desacetylcolchicine
- Reichstein's F
- Santavy's substance F
- Definition
- A secondary amino compound that is (S)-colchicine in which the N-acetyl group is replaced by an N-methyl group. Isolable from the autumn crocus, Colchicum autumnale, it is less toxic than colchicine and is used as an antineoplastic.
- References
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- CAS:477-30-5
- Drug_Central:4375
- KEGG:C11250
- KNApSAcK:C00027138
- LINCS:LSM-6590
- PMID:1061646
- PMID:20082301
- PMID:22394737
- PMID:2329167
- PMID:2977921
- PMID:7237451
- PMID:7720099
- PMID:7887202
- Patent:DE936268
- Reaxys:2822892
- Wikipedia:Demecolcine
- Ontology
- ChEBI ( EBI )
- Resources
- CTD
- is a type of
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- has_role
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Phenotype
Phenotype resulting from (-)-demecolcine
Phenotype where environments contain (-)-demecolcine
Phenotype modified by environments containing (-)-demecolcine
Human Disease Model