Search Ontology:
ChEBI

fasudil

Term ID
CHEBI:43871
Synonyms
  • 1-(5-isoquinolinesulfonyl)homopiperazine
  • 5-(1,4-diazepan-1-ylsulfonyl)isoquinoline
  • 5-[(hexahydro-1H-1,4-diazepin-1-yl)sulfonyl]isoquinoline
  • AT 877
  • AT-877
  • fasudil
  • fasudilum
  • HA 1077
  • HA-1077
  • HA1077
  • hexahydro-1-(5-isoquinolinesulfonyl)-1H-1,4-diazepine
  • hexahydro-1-(5-isoquinolinylsulfonyl)-1H-1,4-diazepine
  • ZK-258594
Definition
An isoquinoline substituted by a (1,4-diazepan-1-yl)sulfonyl group at position 5. It is a Rho-kinase inhibitor and its hydrochloride hydrate form is approved for the treatment of cerebral vasospasm and cerebral ischemia.
References
Ontology
ChEBI  ( EBI )
Resources
CTD
Relationships
is a type of
has_role
inverse is_conjugate_acid_of
is_conjugate_base_of
Phenotype
Phenotype resulting from fasudil
Phenotype where environments contain fasudil
Phenotype modified by environments containing fasudil
Human Disease Model