Search Ontology:
ChEBI
fasudil
- Term ID
- CHEBI:43871
- Synonyms
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- 1-(5-isoquinolinesulfonyl)homopiperazine
- 5-(1,4-diazepan-1-ylsulfonyl)isoquinoline
- 5-[(hexahydro-1H-1,4-diazepin-1-yl)sulfonyl]isoquinoline
- AT 877
- AT-877
- fasudil
- fasudilum
- HA 1077
- HA-1077
- HA1077
- hexahydro-1-(5-isoquinolinesulfonyl)-1H-1,4-diazepine
- hexahydro-1-(5-isoquinolinylsulfonyl)-1H-1,4-diazepine
- ZK-258594
- Definition
- An isoquinoline substituted by a (1,4-diazepan-1-yl)sulfonyl group at position 5. It is a Rho-kinase inhibitor and its hydrochloride hydrate form is approved for the treatment of cerebral vasospasm and cerebral ischemia.
- References
-
- CAS:103745-39-7
- Chemspider:3426
- DrugBank:DB08162
- Drug_Central:1132
- HMDB:HMDB0252175
- KEGG:D07941
- LINCS:LSM-3715
- PDBeChem:M77
- PMID:22363408
- PMID:31670380
- PMID:31894538
- PMID:32076619
- PMID:32192772
- PMID:32396545
- PMID:32462797
- PMID:32650141
- PMID:32685556
- PMID:32727014
- PMID:32770034
- PMID:33222274
- PMID:33341946
- PMID:33357780
- PMID:33433459
- PMID:33436060
- PMID:33527868
- PMID:33832886
- PMID:33838256
- PMID:33907042
- PMID:34078832
- PMID:34156163
- PMID:34239271
- PMID:34359853
- PMID:34384329
- PMID:34542824
- PMID:34557101
- PMID:34558416
- Wikipedia:Fasudil
- Ontology
- ChEBI ( EBI )
- Resources
- CTD
- is a type of
-
- has_role
- inverse is_conjugate_acid_of
-
- is_conjugate_base_of
-
Phenotype
Phenotype resulting from fasudil
Phenotype where environments contain fasudil
Phenotype modified by environments containing fasudil
Human Disease Model