delavirdine mesylate

Term ID

CHEBI:4379

Synonyms

• 1-(3-(isopropylamino)-2-pyridyl)-4-((5-methanesulfonamidoindol-2-yl)carbonyl)piperazine monomethanesulfonate
• Delavirdine mesilate
• Delavirdine mesylate
• delavirdine methanesulfonate
• delavirdine monomethanesulfonate
• N-[2-({4-[3-(propan-2-ylamino)pyridin-2-yl]piperazin-1-yl}carbonyl)-1H-indol-5-yl]methanesulfonamide methanesulfonate
• N-{2-[4-(3-Isopropylamino-pyridin-2-yl)-piperazine-1-carbonyl]-1H-indol-5-yl}-methanesulfonamide; compound with methanesulfonic acid

Definition

The monomethanesulfonic acid salt of delavirdine, a non-nucleoside reverse transcriptase inhibitor with activity specific for HIV-1. Viral resistance emerges rapidly when delavirdine is used alone, so it is therefore used (as the methanesulfonic acid salt) with other antiretrovirals for combination therapy of HIV infection.

References

• Beilstein:7617470
• CAS:147221-93-0
• KEGG:C08087
• KEGG:D00895

Ontology

ChEBI  ( EBI )