Search Ontology:
ChEBI
3-(5-fluorouracil-1-yl)-L-alanine
- Term ID
- CHEBI:42549
- Synonyms
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- (2S)-2-amino-3-(5-fluoro-2,4-dioxo-1,2,3,4-tetrahydropyrimidin-1-yl)propanoic acid
- (S)-(-)-5-fluorowillardiine
- (S)-alpha-Amino-5-fluoro-3,4-dihydro-2,4-dioxo-1(2H)-pyrimmidinepropanoic acid
- (S)-F-Willardiine
- 2-AMINO-3-(5-FLUORO-2,4-DIOXO-3,4-DIHYDRO-2H-PYRIMIDIN-1-YL)-PROPIONIC ACID
- 3-(5-fluoro-2,4-dioxo-3,4-dihydropyrimidin-1(2H)-yl)-L-alanine
- 5-Fluorowillardiine
- Definition
- An alanine derivative that is L-alanine bearing a 5-fluorouracil-1-yl substituent at position 3. A more potent and selective AMPA receptor agonist (at hGluR1 and hGluR2) than AMPA itself (Ki = 14.7, 25.1, and 1820 nM for hGluR1, hGluR2 and hGluR5 respectively).
- References
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- CAS:140187-23-1
- DrugBank:DB02966
- KEGG:C13671
- PDBeChem:FWD
- PMID:11041846
- PMID:11487516
- PMID:1371315
- PMID:16256076
- PMID:7566471
- PMID:8640342
- PMID:8957243
- Reaxys:7817206
- Wikipedia:5-Fluorowillardiine
- Ontology
- ChEBI ( EBI )
- Resources
- CTD
- is a type of
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- has_functional_parent
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- has_role
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Show first 5 Terms
Phenotype
Phenotype resulting from 3-(5-fluorouracil-1-yl)-L-alanine
Phenotype where environments contain 3-(5-fluorouracil-1-yl)-L-alanine
Phenotype modified by environments containing 3-(5-fluorouracil-1-yl)-L-alanine
Human Disease Model