(R,R)-5,11-diethyl-5,6,11,12-tetrahydro-2,8-chrysenediol

Term ID

CHEBI:42371

Synonyms

• (5R,11R)-5,11-diethyl-5,6,11,12-tetrahydrochrysene-2,8-diol
• (R,R)-5,11-cis-diethyl-5,6,11,12-tetrahydrochrysene-2,8-diol
• (R,R)-cis-diethyl tetrahydro-2,8-chrysenediol
• (R,R)-cis-diethyltetrahydro-2,8-chrysenediol
• (R,R)-THC
• R,R-THC

Definition

A carbotetracyclic compound that is 5,6,11,12-tetrahydrochrysene substituted by hydroxy groups at positions 2 and 8 and by ethyl groups at positions 5 and 11 (the 5R,11R-stereoisomer). It is an agonist of ER-alpha and antagonist of ER-beta receptors.

References

• CAS:221368-54-3
• Chemspider:394097
• PDBeChem:ETC
• PMID:11953755
• PMID:15582497
• PMID:18719660
• PMID:19505948
• PMID:20097735
• PMID:21940647
• PMID:22099601
• PMID:23688559
• PMID:23857051
• PMID:24134630
• PMID:25167991
• PMID:26855429
• Wikipedia:(R,R)-Tetrahydrochrysene

Ontology

ChEBI  ( EBI )